In many patients with epilepsy, seizures can be controlled with the established antiepilepstic drugs (Brodie et al., 1996) but 25-30% of patients continue to have seizures despite optional therapy, and other have unacceptable side effects. Thus there is clearly a need for additional drugs as well as formant. Strategies for preventing epilepsy. Mechanisms is that underline seizure processes constitute potential target areas for the development of new AEDS. New antiepileptics drugs (AEDS) are being developed using two complimentary strategies. Animal models that roughly mania human used to serene new compounds for antiseizure activity. Alternatively, new drugs are being developed with specific cellular or molecular targets believed to be important in seizure generation.
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